Lone Wolf: Vengeance of the Kai is an asymmetrical 2-player strategy game set in the world of Lone Wolf - the fantasy setting of the series first launched 40 years ago. It encompasses the storyline of the first 12 books in the series, allowing players to relive the decisive battle between good (Lone Wolf and the Freeland Alliance) and evil (the Darklords of Helgedad and their allies) for the fate of Magnamund, with different outcomes every time.

The game lasts 6 rounds, with each side pursuing different objectives to win. Game rounds consist of 3 phases - the Action Phase, Quest Phase and Refresh Phase.

The Freeland Alliance begins the game with less resources (troops, gold) and must survive long enough for Lone Wolf to succeed at five (5) Quests to recover the power and wisdom of his slaughtered Order (the Kai Lords of Sommerlund) to destroy the Darklords.

The Darklords possess a more powerful army and greater wealth, which they must use to conquer 5 of 9 strategic Freeland capitals before Lone Wolf succeeds at his Quests. If neither side achieves their objective by the end of the 6th game round, the winner is determined by whoever accumulated more Victory Points, which are gained by succeeding at Quests (Freeland Alliance only), controlling strategic capitals or damaging/destroying enemy Leaders. The game has multiple sources of variability - mix of Leaders, starting territories, card draws - that allow for endless re-playability (no 2 games will ever be the same). The game play is tense, with every action a trade-off between advancing your own agenda or hindering your opponent's. Seemingly inconsequential actions taken early in the game often turn out to have major repercussions in later rounds.